Dr Chris Armstrong

Researcher (BSc) PhD, Biochemistry & Molecular Biology, Biochemistry & Molecular Biology, Open Medicine Foundation

Dr Travis Craddock

Nova South Eastern University, Florida

Prof. Jonas Bergquist

MD, PhD, Professor of Analytical Chemistry/Neurochemistry, Department of Chemistry at Uppsala University, Sweden, Department of Pathology, University of Utah, USA.

Christopher Armstrong, PhD, is most well-known for his research using
metabolomics to observe biochemical alterations in ME/CFS patients. Chris published the first ME/CFS metabolomics study on blood and urine in 2015. These studies recognised an alteration in energy, amino acid, purine and oxidative metabolism in ME/CFS patients. In 2017, this work was followed up by observing how these alterations in metabolism were related to changes in gut bacteria and their metabolites. Since then Chris has set up collaborative efforts to apply metabolomic experiments to immunological experiments on ME/CFS, observing how the metabolome may relate to immune cell alteration. He is also focused on cell metabolism and longitudinal research in ME/CFS while looking to extend metabolic capabilities across the field of ME/CFS to help collate different groups researching ME/CFS. Dr Armstrong is a member of the Working Group, which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University.

Travis J.A. Craddock, Ph.D. is an Associate Professor in the Departments of Psychology & Neuroscience, Computer Science and Clinical Immunology at Nova Southeastern University (NSU) in Fort Lauderdale, Florida. He serves as the Director of the Clinical Systems Biology group at NSU’s Institute for Neuro Immune Medicine where he applies computational systems biology and biophysics methods towards the purpose of identifying novel treatments for complex chronic illness involving neuroinflammation. Dr. Craddock received his PhD in the field of biophysics at the University of Alberta where his graduate research activities focused on subneural biomolecular information processing, and nanoscale neuroscience descriptions of memory, consciousness and cognitive dysfunction in neurodegenerative disorders. His current research activities are focused on using a theory driven approach to understand the underlying molecular regulation of chronic illness resulting from exposure to neurotoxins, such as anesthesia and nerve agents, or viral infection in order to improve diagnosis and putative treatment strategies. This work is primarily funded by the U.S. Department of Defense and the National Institutes of
Health.

Prof. Bergquist leads a research group focused on the development of analytical tools for screening and discovery of biomarkers for various pathological states. Prof. Bergquist’s group works to increase understanding of what initiates the disease process to enable early diagnosis. Prof. Bergquist is a member of the Working Group, which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University. Current Areas of Academic Focus: cellular information processes, and molecular neuroscience; biophysics of neurological/neurodegenerative diseases; systems neurobiology; and quantum biology.

Dr Leighton Barnden

Neuroimaging Researcher,
National Centre for Neuroimmunology and Emerging Diseases, Griffith University, Queensland, Australia.

Prof. Paul Fisher

Microbiologist
BSc (Hons), MSc, PhD, Head of Microbiology, Department of Physiology, Anatomy and Microbiology, La Trobe University, Melbourne.

Prof. Sonya M. Marshall-Gradisnik

BSc (Hons), PhD, co-director of the National Centre for Neuroimmunology and Emerging Diseases (NCNED), Menzies Health Institute QLD, Griffith University, Queensland, Australia

Dr Barnden started his career in Nuclear Medicine, but for the last 25 years has specialised in medical image processing. His publications on brain ‘structural’ MRI imaging in CFS reported abnormal autonomic nervous system function and depleted brain stem myelin levels.

Prof. Fisher studies neurodegenerative disease, mitochondrial biology and the roles of mitochondria in disease, using 2 model systems to understand the cytopathological pathways involved. He has advanced expertise in mitochondrial & molecular biology, biochemistry and cell physiology, including the complete array of modern molecular techniques as well as in the diverse statistical methods in the data analysis.

Professor Marshall-Gradisnik’s team and expertise is in CFS/ME with particular focus on Natural Killer Cell, cell signalling pathways, immune cell functions and signalling, gene expression and ion channel function.

Dr Elisha Josev

PhD M.Psych (Clinical Neuropsychology), Murdoch Children’s Research Institute

Dr Robert D. Phair

PhD, Co-founder and Chief Science Officer, Integrative Bioinformatics, Inc

Dr Neil McGregor

(BDS, MDSc, PhD), Periodontist Honorary Senior Fellow, University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences

Dr Elisha Josev is an early career postdoctoral researcher at the Murdoch Children’s Research Institute. She holds a PhD and a Masters of Psychology (Clinical Neuropsychology) from the University of Melbourne, and is a registered psychologist. She has a revealed activin B as a serum biomarker of significant potential, as well as the development of the weighted standing time (WST) as a
simple proxy for ME/CFS symptom severity. Additionally, important observations were made on comorbid POTS, and via machine learning and statisitical analyses, redefinition of routine pathology markers as screening tools.

Dr Phair is an MIT electrical engineer with a PhD in (cardiovascular) physiology. After post-docs in computer modelling and cellular endocrinology, he was a professor of physiology and of biomedical engineering at The Johns Hopkins School of Medicine for 16 years. In 2001, he co-founded Integrative Bioinformatics Inc, a scientific consulting and software development firm in Silicon Valley where he is Chief Science Officer. Dr Phair has built mechanistic computer models and performed experiments at levels of biological organization from physiology to biochemistry to molecular cell biology. About 3 years ago he met Dr Ron Davis and joined the quest to cure ME/CFS. Dr Phair is the originator of the metabolic trap concept and will tell us about Metabolic Traps in ME/CFS.

Dr McGregor is a highly experienced ME/CFS researcher, having coauthored
more than 40 papers in ME/CFS, over a period of more than 20 years. He has been involved in research both in Australia and in the. U.S. including chronic pain aetiology and treatment, chronic viral infections and viral reactivation processes and treatments, bacterial/host immune interactions and the resultant host pathology and the development of instruments to measure human pathology. He is an expert in analysis of metabolomes. Dr. McGregor is a member of the Working Group, which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University.

Dr Brett Lidbury

Associate Professor
National Centre for Epidemiology and Population Health, Research School of Population Health, The Australian National University (ANU) College of Health and Medicine.

Dr Nicole Phillips

Clinician

Dr Lisa McLindon-Smith

Clinician

Dr Lidbury came to ME/CFS research via fundamental experimental investigations into arboviral pathogenesis, particularly for Ross River Virus (RRV), a long-suspected pathogen in Australian cases of ME/CFS. These fundamental studies revealed several mechanisms of immune manipulation and evasion associated with host macrophages, including RRV persistence strategies, and the ablation of early proinflammatory activity post antibodydependent enhancement (ADE). A relationship with CFS Discovery (Melbourne) commenced in 2010 – 11, and led to the completion of two projects – the first a pilot study funded by the Alison Hunter Memorial Foundation, and a recently completed project funded by the Judith J. Mason Foundation. Together, the results of these projects and treatment, chronic viral infections and viral reactivation processes and treatments, bacterial/host immune interactions and the resultant host pathology and the development of instruments to measure human pathology. He is an expert in analysis of metabolomes. Dr. McGregor is a member of the Working Group, which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University.

Dr Phillips is a psychiatrist in private Clinician practice in Armadale, Victoria. She graduated from Auckland Medical School, then completed diplomas in family planning and obstetrics in Melbourne before entering psychiatry specialty training. She has been a fellow of the Royal Australian & N.Z. College of Psychiatrists since 1994. Nicole’s main professional interests are women’s mental health, medicolegal assessments and ME/CFS. In the 1980s & 1990s she established and ran an innovative psychiatric referral and consultation service at the Mercy Hospital for Women whilst working on the Mother-Baby Unit for post-natal depression. She was thrown into the world of ME/CFS in 1989, when she developed the illness, and after her recovery some years later, vowed to help others with the illness. From 2001-2013, she was medical advisor to ME/CFS Australia (now Emerge Australia), and was medical editor of The Emerge Journal. Nicole has spoken at many meetings and conferences, addressed a parliamentary forum, and has been interviewed by the media many times, including ABC’s Mind Matters. She has a number of CFS patients in her practice. Her approach to the management of all her patients, no matter what the diagnosis, is holistic.

Dr McLindon-Smith is a qualified Medical Practitioner and Teacher.
After postgraduate years in hospital medicine, Dr Lisa then went on to train in Naprotechnology, and became Melbourne’s first Medical Consultant in this field. Her areas of expertise in private practice have been recurrent miscarriage,
subfertility, infertility and women’s health. Further areas of long term interest are ME/CFS, adrenal fatigue, chronic pain, & the treatment of the secondary anxiety and depression often associated with these conditions. Dr Lisa has suffered herself from ME/CFS since the age of seventeen. Having had to reduce her clinical hours of recent years she is now busy perfecting both the art & science of managing ME/CFS, and a busy family life. She is a wife to Christopher, and
mother of their five beautiful children.

Dr Luis Nacul

Clinical Associate Professor London School of Hygiene and Tropical Medicine, UK

Prof. Donald R. Staines

MBBS, MPH, FAFPHM, FAFOEM

Dr Wenzhong Xiao

Ph.D. Assistant Professor

Dr Nacul leads the ME/CFS Biobank UK and CureME Team. The team is
driving research for the recognition, diagnosis and treatment of ME and
CFS. He serves as a Member Substitute for EUROMENE, an international not for profit organization for ME/CFS research. In 2018 Dr Nacul was appointed to the review committee for the NICE guidelines for ME/CFS used by the British NHS.

Prof. Donald R. Staines is a Clinical Professor at Menzies Health Institute Queensland and the co-director (alongside Professor Sonya Marshall-Gradisnik) of the National Centre for Neuroimmunology and Emerging Diseases (NCNED), Menzies Health Institute Queensland, Griffith University, Queensland, Australia

Bioinformatics at Harvard Medical School and director of the Inflammation & Metabolism Computational Center at Massachusetts General Hospital.

Dr Alain Moreau

PhD

Dr Cara Tomas

Research Associate Newcastle University, UK

Dr Don Lewis

Clinician

Dr Moreau’s chief interests of study are pediatric scoliosis, osteoarthritis,
osteoporosis, and Myalgic Encephalomyelitis. Dr Moreau is a member of the Working Group, which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University. Professor Moreau’s
research team has developed an innovative test to reproduce postexertional
malaise, which led to a molecular stratification of ME/CFS patients using a panel of circulating microRNAs. He is investigating genetic and epigenetic determinants of ME/CFS.

Dr Cara Tomas completed a master’s degree looking at the role of pyruvate
dehydrogenase in ME/CFS before completing her PhD in 2018 researching the role of cellular bioenergetics in ME/CFS. Cara is also a ME/CFS patient and therefore can approach the subject from both a researcher and from a patient perspective. Her publications in ME/CFS cover various aspects of the disease including HPA axis dysfunction, cardiac abnormalities, mitochondrial function, and biomarkers.

Dr Lewis’s interest in ME/CFS began in 1985 and has steadily progressed
since that time. In 2001, the CFS Discovery clinic was established, being a facility where attention is directed solely to the management of people with this illness. In addition to establishing a protocol leading to diagnosis and relevant investigations to uncover the mechanism of this illness, patients attending also
became ready subjects for many research projects that are covered in the past than currently in conjunction with five universities. This has led to the formation of ME/CFS Discovery Research Network (MDRN), which is forming the harbour supporting these tertiary institutes in their current and foreseeable research, and providing information of the advanced research work conducted by various bodies in Melbourne and Australia

2019 Research Symposium Speakers

Click on a speakers name below to find our more and access their keynote video.

Researcher (BSc) PhD, Biochemistry & Molecular Biology, Biochemistry & Molecular Biology, Open Medicine Foundation

Christopher Armstrong, PhD, is most well-known for his research using metabolomics to observe biochemical alterations in ME/CFS patients. Chris published the first ME/CFS metabolomics study on blood and urine in 2015. These studies recognised an alteration in energy, amino acid, purine and oxidative metabolism in ME/CFS patients. In 2017, this work was followed up by observing how these alterations in metabolism were related to changes in gut bacteria and their metabolites. Since then Chris has set up collaborative efforts to apply metabolomic experiments to immunological experiments on ME/CFS, observing how the metabolome may relate to immune cell alteration. He is also focused on cell metabolism and longitudinal research in ME/CFS while looking to extend metabolic capabilities across the field of ME/CFS to help collate different groups researching ME/CFS. Dr Armstrong is a member of the Working Group, which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University.

Nova South Eastern University, Florida

Travis J.A. Craddock, Ph.D. is an Associate Professor in the Departments of Psychology & Neuroscience, Computer Science and Clinical Immunology at Nova Southeastern University (NSU) in Fort Lauderdale, Florida. He serves as the Director of the Clinical Systems Biology group at NSU’s Institute for Neuro Immune Medicine where he applies computational systems biology and biophysics methods towards the purpose of identifying novel treatments for complex chronic illness involving neuroinflammation. Dr. Craddock received his PhD in the field of biophysics at the University of Alberta where his graduate research activities focused on subneural biomolecular information processing, and nanoscale neuroscience descriptions of memory, consciousness and cognitive dysfunction in neurodegenerative disorders. His current research activities are focused on using a theory driven approach to understand the underlying molecular regulation of chronic illness resulting from exposure to neurotoxins, such as anesthesia and nerve agents, or viral infection in order to improve diagnosis and putative treatment strategies. This work is primarily funded by the U.S. Department of Defense and the National Institutes of
Health.

MD, PhD, Professor of Analytical Chemistry/Neurochemistry, Department of Chemistry at Uppsala University, Sweden, Department of Pathology, University of Utah, USA.

Prof. Bergquist leads a research group focused on the development of analytical tools for screening and discovery of biomarkers for various pathological states. Prof. Bergquist’s group works to increase understanding of what initiates the disease process to enable early diagnosis. Prof. Bergquist is a member of the Working Group, which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University. Current Areas of Academic Focus: cellular information processes, and molecular neuroscience; biophysics of neurological/neurodegenerative diseases; systems neurobiology; and quantum biology.

Neuroimaging Researcher,
National Centre for Neuroimmunology and Emerging Diseases, Griffith University, Queensland, Australia.

Dr Barnden started his career in Nuclear Medicine, but for the last 25 years has specialised in medical image processing. His publications on brain ‘structural’ MRI imaging in CFS reported abnormal autonomic nervous system function and depleted brain stem myelin levels.

Microbiologist
BSc (Hons), MSc, PhD, Head of Microbiology, Department of Physiology, Anatomy and Microbiology, La Trobe University, Melbourne.

Prof. Fisher studies neurodegenerative disease, mitochondrial biology and the roles of mitochondria in disease, using 2 model systems to understand the cytopathological pathways involved. He has advanced expertise in mitochondrial & molecular biology, biochemistry and cell physiology, including the complete array of modern molecular techniques as well as in the diverse statistical methods in the data analysis.

BSc (Hons), PhD, co-director of the National Centre for Neuroimmunology and Emerging Diseases (NCNED), Menzies Health Institute QLD, Griffith University, Queensland, Australia

Professor Marshall-Gradisnik’s team and expertise is in CFS/ME with particular focus on Natural Killer Cell, cell signalling pathways, immune cell functions and signalling, gene expression and ion channel function.

PhD M.Psych (Clinical Neuropsychology), Murdoch Children’s Research Institute

Dr Elisha Josev is an early career postdoctoral researcher at the Murdoch Children’s Research Institute. She holds a PhD and a Masters of Psychology (Clinical Neuropsychology) from the University of Melbourne, and is a registered psychologist. She has a revealed activin B as a serum biomarker of significant potential, as well as the development of the weighted standing time (WST) as a
simple proxy for ME/CFS symptom severity. Additionally, important observations were made on comorbid POTS, and via machine learning and statisitical analyses, redefinition of routine pathology markers as screening tools.

PhD, Co-founder and Chief Science Officer, Integrative Bioinformatics, Inc

Dr Phair is an MIT electrical engineer with a PhD in (cardiovascular) physiology. After post-docs in computer modelling and cellular endocrinology, he was a professor of physiology and of biomedical engineering at The Johns Hopkins School of Medicine for 16 years. In 2001, he co-founded Integrative Bioinformatics Inc, a scientific consulting and software development firm in Silicon Valley where he is Chief Science Officer. Dr Phair has built mechanistic computer models and performed experiments at levels of biological organization from physiology to biochemistry to molecular cell biology. About 3 years ago he met Dr Ron Davis and joined the quest to cure ME/CFS. Dr Phair is the originator of the metabolic trap concept and will tell us about Metabolic Traps in ME/CFS.

(BDS, MDSc, PhD), Periodontist Honorary Senior Fellow, University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences

Dr McGregor is a highly experienced ME/CFS researcher, having coauthored
more than 40 papers in ME/CFS, over a period of more than 20 years. He has been involved in research both in Australia and in the. U.S. including chronic pain aetiology and treatment, chronic viral infections and viral reactivation processes and treatments, bacterial/host immune interactions and the resultant host pathology and the development of instruments to measure human pathology. He is an expert in analysis of metabolomes. Dr. McGregor is a member of the Working Group, which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University.

Associate Professor
National Centre for Epidemiology and Population Health, Research School of Population Health, The Australian National University (ANU) College of Health and Medicine.

Dr Lidbury came to ME/CFS research via fundamental experimental investigations into arboviral pathogenesis, particularly for Ross River Virus (RRV), a long-suspected pathogen in Australian cases of ME/CFS. These fundamental studies revealed several mechanisms of immune manipulation and evasion associated with host macrophages, including RRV persistence strategies, and the ablation of early proinflammatory activity post antibodydependent enhancement (ADE). A relationship with CFS Discovery (Melbourne) commenced in 2010 – 11, and led to the completion of two projects – the first a pilot study funded by the Alison Hunter Memorial Foundation, and a recently completed project funded by the Judith J. Mason Foundation. Together, the results of these projects and treatment, chronic viral infections and viral reactivation processes and treatments, bacterial/host immune interactions and the resultant host pathology and the development of instruments to measure human pathology. He is an expert in analysis of metabolomes. Dr. McGregor is a member of the Working Group, which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University.

Clinician

Dr Phillips is a psychiatrist in private Clinician practice in Armadale, Victoria. She graduated from Auckland Medical School, then completed diplomas in family planning and obstetrics in Melbourne before entering psychiatry specialty training. She has been a fellow of the Royal Australian & N.Z. College of Psychiatrists since 1994. Nicole’s main professional interests are women’s mental health, medicolegal assessments and ME/CFS. In the 1980s & 1990s she established and ran an innovative psychiatric referral and consultation service at the Mercy Hospital for Women whilst working on the Mother-Baby Unit for post-natal depression. She was thrown into the world of ME/CFS in 1989, when she developed the illness, and after her recovery some years later, vowed to help others with the illness. From 2001-2013, she was medical advisor to ME/CFS Australia (now Emerge Australia), and was medical editor of The Emerge Journal. Nicole has spoken at many meetings and conferences, addressed a parliamentary forum, and has been interviewed by the media many times, including ABC’s Mind Matters. She has a number of CFS patients in her practice. Her approach to the management of all her patients, no matter what the diagnosis, is holistic.

Clinician

Dr McLindon-Smith is a qualified Medical Practitioner and Teacher.
After postgraduate years in hospital medicine, Dr Lisa then went on to train in Naprotechnology, and became Melbourne’s first Medical Consultant in this field. Her areas of expertise in private practice have been recurrent miscarriage,
subfertility, infertility and women’s health. Further areas of long term interest are ME/CFS, adrenal fatigue, chronic pain, & the treatment of the secondary anxiety and depression often associated with these conditions. Dr Lisa has suffered herself from ME/CFS since the age of seventeen. Having had to reduce her clinical hours of recent years she is now busy perfecting both the art & science of managing ME/CFS, and a busy family life. She is a wife to Christopher, and
mother of their five beautiful children.

Clinical Associate Professor London School of Hygiene and Tropical Medicine, UK

Dr Nacul leads the ME/CFS Biobank UK and CureME Team. The team is
driving research for the recognition, diagnosis and treatment of ME and
CFS. He serves as a Member Substitute for EUROMENE, an international not for profit organization for ME/CFS research. In 2018 Dr Nacul was appointed to the review committee for the NICE guidelines for ME/CFS used by the British NHS.

MBBS, MPH, FAFPHM, FAFOEM

Prof. Donald R. Staines is a Clinical Professor at Menzies Health Institute Queensland and the co-director (alongside Professor Sonya Marshall-Gradisnik) of the National Centre for Neuroimmunology and Emerging Diseases (NCNED), Menzies Health Institute Queensland, Griffith University, Queensland, Australia

Ph.D. Assistant Professor

Bioinformatics at Harvard Medical School and director of the Inflammation & Metabolism Computational Center at Massachusetts General Hospital.

Dr Moreau’s chief interests of study are pediatric scoliosis, osteoarthritis,
osteoporosis, and Myalgic Encephalomyelitis. Dr Moreau is a member of the Working Group, which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University. Professor Moreau’s
research team has developed an innovative test to reproduce postexertional
malaise, which led to a molecular stratification of ME/CFS patients using a panel of circulating microRNAs. He is investigating genetic and epigenetic determinants of ME/CFS.

Research Associate Newcastle University, UK

Dr Cara Tomas completed a master’s degree looking at the role of pyruvate
dehydrogenase in ME/CFS before completing her PhD in 2018 researching the role of cellular bioenergetics in ME/CFS. Cara is also a ME/CFS patient and therefore can approach the subject from both a researcher and from a patient perspective. Her publications in ME/CFS cover various aspects of the disease including HPA axis dysfunction, cardiac abnormalities, mitochondrial function, and biomarkers.

Clinician

Dr Lewis’s interest in ME/CFS began in 1985 and has steadily progressed
since that time. In 2001, the CFS Discovery clinic was established, being a facility where attention is directed solely to the management of people with this illness. In addition to establishing a protocol leading to diagnosis and relevant investigations to uncover the mechanism of this illness, patients attending also
became ready subjects for many research projects that are covered in the past than currently in conjunction with five universities. This has led to the formation of ME/CFS Discovery Research Network (MDRN), which is forming the harbour supporting these tertiary institutes in their current and foreseeable research, and providing information of the advanced research work conducted by various bodies in Melbourne and Australia

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